So, after I have a reasonably decent layout, I then actually pencil in each panel. Since this comic is done mostly digitally, I often draw each character individually and then place them on the page later in photoshop, or other times I'll simply draw the whole panel, such as the example below.
I then scan the penciled images into the computer. I lay the page panels out in Photoshop, and then place the scanned drawings in onto the panels, and arrange the page exactly how I want it laid out. It's pretty quick if I have the panels all drawn out already but can take a while if I drew everything separately. Then, I take out my trusty Wacom tablet and begin to draw the final product.
Next time: What I do after I pencil like an idiot